2-METHYL-AP-237 [EUROPE TO WORLDWIDE]

Hey, We are MicroDroper team. 7 years in the Dark Market. Over 16k reviews. 100% satisfaction. We are working with TGC labs (tgchemicals.com) and here to provide for you the best quality of research chemicals on the Darknet. Seems like Nemesis market is the best market place. Our team hope to have good relationships in this market and hopefully they will stay up for a long run!

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Bucinnazine (AP-237, 1-butyryl-4-cinnamylpiperazine) is an opioid analgesic drug that was widely used in China to treat pain in cancer patients as of 1986. It is one of the most potent compounds among a series of piperazine-amides first synthesized and reported in Japan in the 1970s. Bucinnazine has analgesic potency comparable to that of morphine but with a relatively higher therapeutic index.

The drug was initially claimed to be a non-narcotic analgesic. However, subsequent studies have shown bucinnazine and similar acyl piperazines to be potent and selective agonists of μ-opioid receptor (MOR) with relatively low affinity for the δ-opioid receptor and the κ-opioid receptor. In accordance with these studies, results from the intravenous self-administration experiments in rats showed that bucinnazine has a marked reinforcing effect with tolerance and dependence quickly developing. In addition, the morphine antagonist naloxone reverses the effect of bucinnazine and precipitates withdrawal symptoms in bucinnazine treated rats further indicating a mechanism of analgesia mediated via selective agonist activity at μ-opioid receptors.

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We ship worldwide (unless stated otherwise) with a near 100% success rate due to dedication to solid stealth. If for some reason your parcel does get confiscated, lost or anything else happens we will reship ONCE for free.

MINIMUM ORDER = 2 grams. Please do not ask for lower amount. Thanks!

Europe: 1-7 days
USA: 4-16 days
Rest of the world: 6-24 days

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Allow us up to 48h to properly send out your orders please. We can have extremely busy periods and we work with a small team so please have a little patience as it will work positively for both parties. We don’t want to make mistakes and so we would rather take a little longer to double check everything before we ship it out!